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Gallery of gametocytes

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Gallery of Gametocytes
Gametocytes essentially have "microgametocyte" (male) or "macrogametocyte" (female) appearance. For most species the gametocyte is round or slightly angular with species differences mainly reflected in the size of the red cell or parasite, although red cell dots may be seen in P.vivax or P.ovale. The exception is the P.falciparum parasite that has an elongated rod form that may become curved by the residual erythroid membrane - sometimes called the "banana" form..

P.falciparum
Rod shaped gametocytes may be straingh and blunt (mainly the shorter "microgametocytes") or curved by the red cell membrane producing a curved and more pointed end (banana form). Pigment generally overlies the central chromatin area.

  • Macrogametocyte, curved by the red cell membrane

    Macrogametocyte, curved by the red cell membrane

  • Microgametocytes, a blunt rod, red cell membrane is "floppy"

    Microgametocytes, a blunt rod, red cell membrane is "floppy"

  • A more sharp-ended curved macrogametocyte

    A more sharp-ended curved macrogametocyte

"

P.vivax
As with other forms in this species parasites and infected red cells are characteristically large; Schüffner's may be seen or hidden by the parasite for macrogametocyte forms. Parasites may have an irregular shape; pigment distribution is diffuse. Images show a maturing sequence.

  • A large and irregular macrogmetocyte

    A large and irregular macrogmetocyte

  • Large macrogametocyte fills red cell

    Large macrogametocyte fills red cell

  • Microgametocytes with Schüffner's dots visible in red cell cytoplasm

    Microgametocytes with Schüffner's dots visible in red cell cytoplasm

"

P.ovale
Similar to P.vivax but generally smaller and the red cell will often show features such as James' dots, fimbriation and ovoid shape. Pigment tends to be around the circumference of the parasite.

  • Elongated and ovoid red cell contains the parasite

    Elongated and ovoid red cell contains the parasite

  • Small round parasite with prominent James' dots

    Small round parasite with prominent James' dots

  • A more typically ovoid form

    A more typically ovoid form

  • Round parasite note the pigment around the circumference

    Round parasite note the pigment around the circumference

"

P.malariae
Small and neat parasites that do not fill the the red cell. Neat pigment around the parasite circumference, Zeimann's dots rarely seen.

  • Small round with circumferential pigment

    Small round with circumferential pigment

  • A neat round, possible macrogametocyte form

    A neat round, possible macrogametocyte form

  • Very small and red cell parasite (possible microgametocyte)

    Very small and red cell parasite (possible microgametocyte)

  • Small gametocyte, possibly a second ring form within the cell

    Small gametocyte, possibly a second ring form within the cell

"

P.knowlesi
Gametocytes are most similar in appearance to P.malariae. Small and generally round.

  • Small and slightly degenerate gametocyte

    Small and slightly degenerate gametocyte

  • Similar appearance note small size and absent dots

    Similar appearance note small size and absent dots

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