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Species identification: summary page

From MalariaETC


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This page presents a broad outline of those species that cause malaria in humans, together with links to more detaile descriptions.


Plasmodium falciparum



Summary: The ring trophozoites are small and fine with typical accolé forms, multiple parasites per cell, and double dot forms. Red cells aquire characteristic Maurer's dots and clefts in late trophozoites. Schizonts are rarely seen in blood, while gametocytes are characteristicaly elongated (and often curved).
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Plasmodium vivax



Summary: Large and robust rings may become "amoeboid" in shape during later development. The red cells become increasingly enlarged and distorted and Schüffner's dots are increasingly visible in cytoplams. All forms tend to circulate with large schizont and gametocyte forms present.
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Plasmodium ovale



Summary: Trophozites tend to retain a ring appearance but are large and robust. Red cells become moderately enlarged and may have oval shape and/or characteristic fimbriation. Expect James' dots to be easily seen in appropriately stained samples. Cases may be difficult to distinguish morphologically from P.vivax.
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Plasmodium malariae



Summary: The species has small ring forms that are less delicate than P.falciparum and which becoming elongated or solid as parasites mature. Red cells are often small retaining their round shape most often with no added dots. Parasite number is often low, but all forms tend to circulate. Look for the characteristic "daisy" schizonts and small round gametocytes
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Plasmodium knowlesi



Summary: This species has a very limited geographical distribution within S.E Asia. The early trophozoites resemble those of P.falciparum and may have high parasite count, while later rings are more solid or elongated similar to P.malariae, as do schizonts & gametocytes (although less "neat"). Characteristically red cell size is unaffected, although distortion and cytoplasmic dots may be present.
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