https://haematologyetc.org/index.php?action=history&feed=atom&title=Practical_reasons_for_test_failure_1Practical reasons for test failure 1 - Revision history2026-11-08T03:15:03ZRevision history for this page on the wikiMediaWiki 1.41.1https://haematologyetc.org/index.php?title=Practical_reasons_for_test_failure_1&diff=3602&oldid=prevAdmin: Created page with "{{DISPLAYTITLE:<span style="position: absolute; clip: rect(1px 1px 1px 1px); clip: rect(1px, 1px, 1px, 1px);">{{FULLPAGENAME}}</span>}} ---- '''Navigation'''</br> <span style="font-size:90%">Main Malaria Index''</span></br> <span style="font-size:90%">>RDT main page''</span></br> <span style="font-size:90%">>>Multi Band Tests''</span></br> <span style="font-size:90%">>>>Curr..."2025-04-14T14:21:32Z<p>Created page with "{{DISPLAYTITLE:<span style="position: absolute; clip: rect(1px 1px 1px 1px); clip: rect(1px, 1px, 1px, 1px);">{{FULLPAGENAME}}</span>}} ---- '''Navigation'''</br> <span style="font-size:90%"><a href="/index.php?title=MalariaETC_Index" title="MalariaETC Index">Main Malaria Index</a>''</span></br> <span style="font-size:90%">><a href="/index.php?title=Rapid_diagnostic_tests_(RDTs)" title="Rapid diagnostic tests (RDTs)">RDT main page</a>''</span></br> <span style="font-size:90%">>><a href="/index.php?title=Interpretation_guide:_MULTI_BAND_tests" title="Interpretation guide: MULTI BAND tests">Multi Band Tests</a>''</span></br> <span style="font-size:90%">>>>Curr..."</p>
<p><b>New page</b></p><div>{{DISPLAYTITLE:<span style="position: absolute; clip: rect(1px 1px 1px 1px); clip: rect(1px, 1px, 1px, 1px);">{{FULLPAGENAME}}</span>}}<br />
----<br />
'''Navigation'''</br><br />
<span style="font-size:90%">[[MalariaETC Index|Main Malaria Index]]''</span></br><br />
<span style="font-size:90%">>[[Rapid diagnostic tests (RDTs)|RDT main page]]''</span></br><br />
<span style="font-size:90%">>>[[Interpretation guide: MULTI BAND tests|Multi Band Tests]]''</span></br><br />
<span style="font-size:90%">>>>Current page: '''Reasons for Test Failure'''</span><br />
----<br />
<br />
{| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"<br />
|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Practical considerations and reasons for test failure'''</span><br />
<br />
<span style="font-size:90%">Bibliography: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652944/], [https://www.who.int/teams/global-malaria-programme/case-management/diagnosis/rapid-diagnostic-tests]</span><br />
<br />
<br />
<span style="font-size:90%">'''1. Selection and procurement of RDTs'''</br><br />
<br />
<span style="font-size:90%">(a) Quality of test design/production. Historically there was significant variation of performance between tests and batches, this has been greatly improved with the WHO pre-qualification testing program that requires a minimum standard of performant, however users are still advised to check the performance of their selected test (see WHO testing information ref 2 above)</br>(b) Lot variability. Variability between different production batches has been observed and should be considered if RDT performance is less good than expected.</br><br />
<br />
<span style="font-size:90%">'''2. Stability and storage issues'''</br><br />
<br />
<span style="font-size:90%">(a) RDTs typically have a shelf-life of 18–24 months providing storage is appropriate.</br>(b) Tests can suffer degradation if stored in inappropriate heat or humidity: generally tests are stable in the range 2–30°C or higher, but these limits may be exceeded in many countries, and continuous product refrigeration to the point of use may not be guaranteed in developing countries.<br />
<br />
<span style="font-size:90%">'''3. Operator training'''</br><br />
<br />
<span style="font-size:90%">(a) Problems in test usage may include inappropriate placement of test reagents or blood sample on RDT.</br>(b) Poor interpretation of faint lines.</br>(c) Inadequate training or reference materials</div>Admin