Phagocytosed malaria pigment Thick - Revision history

Admin at 10:28, 22 March 2025

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Admin at 10:27, 22 March 2025

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	~~<span style="font-size:160%; color:navy">Biology of the Schizont</br></span>~~
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Admin at 10:26, 22 March 2025

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Admin at 10:22, 22 March 2025

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			'''Navigation'''</br>
			<span style="font-size:90%">>[[MalariaETC Index\|Main Malaria Index]]''</span></br>
			<span style="font-size:90%">>>[[Malaria_Biology\|Malaria Biology Index]]''</span></br>
			<span style="font-size:90%">>>>Current page: '''Schizont Biology'''</span>

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			<span style="font-size:160%; color:navy">Biology of the Schizont</br></span>
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	{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"		{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"

Admin: Created page with "---- {| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal" |colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|Malaria pigment is formed by parasites to detoxify the iron portion of digested haemoglobin, appearing as an insoluble brown or golden clump. Following schizont rupture this insoluble material is..."

2025-03-22T10:20:03Z

Created page with "---- {| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal" |colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|'''Phagocytosis of malaria pigment''' ---- Malaria pigment is formed by parasites to detoxify the iron portion of digested haemoglobin, appearing as an insoluble brown or golden clump. Following schizont rupture this insoluble material is..."

New page

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{| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|'''Phagocytosis of malaria pigment'''

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Malaria pigment is formed by parasites to detoxify the iron portion of digested haemoglobin, appearing as an insoluble brown or golden clump. Following schizont rupture this insoluble material is released into the circulation. Below is an image of a rupturing schizont, the red cell membrane will soon lose its integrity releasing both merozoites the pigment (arrowed) will also be released into blood.
<gallery mode="nolines" widths="220px" heights="220px" >
File:Mp1.jpg|Rupturing schizont of ''P.malariae''|link={{filepath:Mp1.jpg}}
</gallery>
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The released pigment is seen as "foreign" material by the immune system and is recognised and ingested by phagocytes (neutrophils or monocytes) where it appears in the cytoplasm and may be visible on thin or thick malaria film preparations. The appearance has some species-specificity, but of more importance when found it should be regarded as evidence to support malaria infection.

<gallery mode="nolines" widths="220px" heights="220px" >
File:Mp2.jpg|Thin film: monocyte pigment|link={{filepath:Mp2.jpg}}
File:Mp3.jpg|Thin film: neutrophil pigment|link={{filepath:Mp3.jpg}}
File:Mp4.jpg|Thick film: neutrophil pigment|link={{filepath:Mp4.jpg}}
</gallery>