Malaria pigment biology - Revision history

Admin at 10:40, 20 March 2025

2025-03-20T10:40:18Z

← Older revision		Revision as of 11:40, 20 March 2025
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	<span style="font-size:90%>'''Additional images'''</span>		<span style="font-size:90%>'''Additional images'''</span>
	<span style="font-size:90%>Pigment in different stages of parasite development</span>		<span style="font-size:90%>Pigment in different stages of parasite development</span>


	<gallery mode="nolines" widths="220px" heights="220px" >		<gallery mode="nolines" widths="220px" heights="220px" >
	File:Pig2.jpg\|<span style="font-size:90%>Gametocyte ''P.malariae''</span>\|link={{filepath:Pig2.jpg}}		File:Pig2.jpg\|<span style="font-size:90%>Gametocyte ''P.malariae''</span>\|link={{filepath:Pig2.jpg}}
	File:Pig3.jpg\|<span style="font-size:90%>Schizont ''P.ovale''</span>\|link={{filepath:Pig3.jpg}}		File:Pig3.jpg\|<span style="font-size:90%>Schizont ''P.ovale''</span>\|link={{filepath:Pig3.jpg}}
	File:Pig4.jpg\|<span style="font-size:90%>Trophozoite ''P.ovale''\|</span>link={{filepath:Pig4.jpg}}		File:Pig4.jpg\|<span style="font-size:90%>Trophozoite ''P.ovale''</span>\|link={{filepath:Pig4.jpg}}
	File:Pig5.jpg\|<span style="font-size:90%>Gametocyte ''P.falciparum''</span>\|link={{filepath:Pig5.jpg}}		File:Pig5.jpg\|<span style="font-size:90%>Gametocyte ''P.falciparum''</span>\|link={{filepath:Pig5.jpg}}
	</gallery>		</gallery>

Admin at 10:39, 20 March 2025

2025-03-20T10:39:23Z

← Older revision		Revision as of 11:39, 20 March 2025
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	</gallery>		</gallery>

	<span style="font-size:90%>'''Image''' A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>		<span style="font-size:90%>'' '''Image''' A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).''</span>


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	<gallery mode="nolines" widths="220px" heights="220px" >		<gallery mode="nolines" widths="220px" heights="220px" >
	File:Pig2.jpg\|Gametocyte ''P.malariae''\|link={{filepath:Pig2.jpg}}		File:Pig2.jpg\|<span style="font-size:90%>Gametocyte ''P.malariae''</span>\|link={{filepath:Pig2.jpg}}
	File:Pig3.jpg\|Schizont ''P.ovale''\|link={{filepath:Pig3.jpg}}		File:Pig3.jpg\|<span style="font-size:90%>Schizont ''P.ovale''</span>\|link={{filepath:Pig3.jpg}}
	File:Pig4.jpg\|Trophozoite ''P.ovale''\|link={{filepath:Pig4.jpg}}		File:Pig4.jpg\|<span style="font-size:90%>Trophozoite ''P.ovale''\|</span>link={{filepath:Pig4.jpg}}
	File:Pig5.jpg\|Gametocyte ''P.falciparum''\|link={{filepath:Pig5.jpg}}		File:Pig5.jpg\|<span style="font-size:90%>Gametocyte ''P.falciparum''</span>\|link={{filepath:Pig5.jpg}}
	</gallery>		</gallery>

Admin at 10:37, 20 March 2025

2025-03-20T10:37:19Z

← Older revision		Revision as of 11:37, 20 March 2025
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	</gallery>		</gallery>

	<span style="font-size:90%>A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>		<span style="font-size:90%>'''Image''' A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>

Admin at 14:37, 27 November 2024

2024-11-27T14:37:48Z

← Older revision		Revision as of 15:37, 27 November 2024
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	<span style=font-size:90%>'''Description'''</span>		<span style=font-size:90%>'''Description'''</span>
	<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>		<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development. When schizonts rupture to release their daughter parasites, the pigment is also released and is takn up by phagocytes.</span>

Admin at 16:37, 19 November 2024

2024-11-19T16:37:01Z

← Older revision		Revision as of 17:37, 19 November 2024
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	<span style="font-size:90%">>>[[Malaria_Biology\|Malaria Biology Index]]''</span></br>		<span style="font-size:90%">>>[[Malaria_Biology\|Malaria Biology Index]]''</span></br>
	<span style="font-size:90%">>>>[[Biology of the trophozoite stage\|Biology of the trophozoite]]</span></br>		<span style="font-size:90%">>>>[[Biology of the trophozoite stage\|Biology of the trophozoite]]</span></br>
	<span style="font-size:90%">>>>Current page: '''Malaria Pigment''' ~~(haemozoin)~~</span>		<span style="font-size:90%">>>>Current page: '''Malaria Pigment'''</span>
	----		----

	{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"		{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
	\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''Malaria Pigment'''</span>		\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''Malaria Pigment''' (haemozoin)</span>
	----		----
	<gallery mode="nolines" widths="220px" heights="220px" >		<gallery mode="nolines" widths="220px" heights="220px" >

Admin at 16:36, 19 November 2024

2024-11-19T16:36:33Z

← Older revision		Revision as of 17:36, 19 November 2024
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	<span style="font-size:90%">>>[[Malaria_Biology\|Malaria Biology Index]]''</span></br>		<span style="font-size:90%">>>[[Malaria_Biology\|Malaria Biology Index]]''</span></br>
	<span style="font-size:90%">>>>[[Biology of the trophozoite stage\|Biology of the trophozoite]]</span></br>		<span style="font-size:90%">>>>[[Biology of the trophozoite stage\|Biology of the trophozoite]]</span></br>
	<span style="font-size:90%">>>>Current page: '''Malaria Pigment'''</span>		<span style="font-size:90%">>>>Current page: '''Malaria Pigment''' (haemozoin)</span>
	----		----

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	<span style=font-size:90%>'''Description'''</span>		<span style=font-size:90%>'''Description'''</span>
	<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "~~haemazoin~~" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>		<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>

Admin at 13:31, 15 November 2024

2024-11-15T13:31:33Z

← Older revision		Revision as of 14:31, 15 November 2024
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	<span style=~~"color:navy;~~font-size:90%>'''Description'''</span>		<span style=font-size:90%>'''Description'''</span>
	<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>		<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>


	<span style="~~color:navy;~~font-size:90%>'''Species significance'''</span>		<span style="font-size:90%>'''Species significance'''</span>
	<span style="font-size:90%>Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.</span>		<span style="font-size:90%>Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.</span>


	<span style="~~color:navy;~~font-size:90%>'''Additional images'''</span>		<span style="font-size:90%>'''Additional images'''</span>
	<span style="font-size:90%>Pigment in different stages of parasite development</span>		<span style="font-size:90%>Pigment in different stages of parasite development</span>

Admin at 13:30, 15 November 2024

2024-11-15T13:30:50Z

← Older revision		Revision as of 14:30, 15 November 2024
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			<span style="color:navy;font-size:90%>'''Species significance'''</span>
			<span style="font-size:90%>Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.</span>


	<span style="color:navy>'''~~Species significance~~'''</span>		<span style="color:navy;font-size:90%>'''Additional images'''</span>
			<span style="font-size:90%>Pigment in different stages of parasite development</span>
	Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.




	<span style="~~color~~:~~navy>'''Additional images'''</span~~>

	Pigment in different stages of parasite development:

Admin at 13:28, 15 November 2024

2024-11-15T13:28:38Z

← Older revision		Revision as of 14:28, 15 November 2024
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	<span style="color:navy>'''Description'''</span>		<span style="color:navy;font-size:90%>'''Description'''</span>


	<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>		<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>

Admin at 13:27, 15 November 2024

2024-11-15T13:27:40Z

← Older revision		Revision as of 14:27, 15 November 2024
Line 15:		Line 15:
	</gallery>		</gallery>

	A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).		<span style="font-size:90%>A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>


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	During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.		<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemazoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.</span>