https://haematologyetc.org/index.php?action=history&feed=atom&title=False_negative_results_and_the_prozone_effect 2026-11-06T19:26:40Z Revision history for this page on the wiki MediaWiki 1.41.1 https://haematologyetc.org/index.php?title=False_negative_results_and_the_prozone_effect&diff=399&oldid=prev 2024-08-29T09:07:11Z

<p>Created page with &quot;{| class=&quot;wikitable&quot; style=&quot;border-style: solid; border-width: 4px; border-color:green&quot; |colspan=&quot;1&quot; style = &quot;font-size:110%; color:black; background: white&quot;|&lt;span style=&quot;color:navy&gt;&lt;/span&gt; The prozone effect is a very rare, but recognised effect that causes false negative results of tests. ---- Most often the prozone effect is seen with HRP2 antigens. This effect means that where these is a &#039;&#039;&#039;very high parasitaemia&#039;&#039;&#039; (causing excess HRP2 antigen to be present) te...&quot;</p> <p><b>New page</b></p><div>{| class=&quot;wikitable&quot; style=&quot;border-style: solid; border-width: 4px; border-color:green&quot;<br /> |colspan=&quot;1&quot; style = &quot;font-size:110%; color:black; background: white&quot;|&lt;span style=&quot;color:navy&gt;&lt;/span&gt;<br /> <br /> <br /> The prozone effect is a very rare, but recognised effect that causes false negative results of tests. <br /> <br /> ----<br /> <br /> Most often the prozone effect is seen with HRP2 antigens. This effect means that where these is a &#039;&#039;&#039;very high parasitaemia&#039;&#039;&#039; (causing excess HRP2 antigen to be present) test can appear negative. It is thought that the presence of excess antigen means that the formation of appropriate antibody-antigen complexes is prevented so that the test does not function correctly.<br /> <br /> <br /> [[Pan-specific antigens in RDTs|Return to pan-specific antibody page]]</div>

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