Amoeboid form main - Revision history

Admin at 17:15, 6 January 2025

2025-01-06T17:15:50Z

← Older revision		Revision as of 18:15, 6 January 2025
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	{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"		{\| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
	\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''Amoeboid forms''' ~~(haemozoin)~~</span>		\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''Amoeboid forms'''</span>
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Admin at 17:14, 6 January 2025

2025-01-06T17:14:31Z

← Older revision		Revision as of 18:14, 6 January 2025
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	<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This ~~form~~ is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.</span>		<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This parasite appearance is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.</span>


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	File:amoeboid2.jpg\|B\|link={{filepath:amoeboid2.jpg}}		File:amoeboid2.jpg\|B\|link={{filepath:amoeboid2.jpg}}
	</gallery>		</gallery>
	<span style="font-size:90%>''Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A)~~, a~~ late trophozoite ~~developing~~ a more typical ~~solid~~ irregular form (B)''		<span style="font-size:90%>''Amoeboid forms: an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A); this late trophozoite has a more typical irregular "amoeboid" form (B)''

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Admin at 17:24, 12 December 2024

2024-12-12T17:24:17Z

← Older revision		Revision as of 18:24, 12 December 2024
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	~~<span style="font-size:90%>~~<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.</span>		<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.</span>

Admin at 17:23, 12 December 2024

2024-12-12T17:23:54Z

← Older revision		Revision as of 18:23, 12 December 2024
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	<span style="font-size:90%>~~A solid~~ and ~~angular late trophozoite~~ form of ''P.~~malariae~~''. ~~Note the golden pigment~~ in ~~separate clumps of granules distributed over the parasite surface (arrowed)~~.</span>		<span style="font-size:90%><span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.</span>


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	</gallery>		</gallery>
	<span style="font-size:90%>''Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)''		<span style="font-size:90%>''Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)''

	<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.

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Admin at 17:22, 12 December 2024

2024-12-12T17:22:24Z

← Older revision		Revision as of 18:22, 12 December 2024
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	<span style="font-size:90%>A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>		<span style="font-size:90%>A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>


	<gallery mode="nolines" widths="220px" heights="220px" >		<gallery mode="nolines" widths="220px" heights="220px" >
	File:~~Pig1~~.jpg\|link={{filepath:~~MPi1~~.jpg}}		File:amoeboid1.jpg\|A\|link={{filepath:amoeboid1.jpg}}
			File:amoeboid2.jpg\|B\|link={{filepath:amoeboid2.jpg}}
	</gallery>		</gallery>
	Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)		<span style="font-size:90%>''Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)''

	<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.		<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.

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Admin at 17:19, 12 December 2024

2024-12-12T17:19:19Z

← Older revision		Revision as of 18:19, 12 December 2024
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	File:Pig1.jpg\|link={{filepath:MPi1.jpg}}		File:Pig1.jpg\|link={{filepath:MPi1.jpg}}
	</gallery>		</gallery>
			Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)

	<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.		<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.


	~~<span style="color:navy>'''Additional images'''</span>~~


	~~<gallery mode="nolines" widths="220px" heights="220px" >~~
	~~File:MAm1.jpg\|A\|link={{filepath:MAm1.jpg}}~~
	~~File:MAm3.jpg\|B\|link={{filepath:MAm3.jpg}}~~
	~~</gallery>~~


	~~Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)~~

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Admin at 17:18, 12 December 2024

2024-12-12T17:18:26Z

@@ Line 13: / Line 13: @@
 |colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|<span style="color:black>'''Amoeboid forms''' (haemozoin)</span>
 ----
 <gallery mode="nolines" widths="220px" heights="220px" >
 File:Pig1.jpg|link={{filepath:MPi1.jpg}}
 </gallery>
-<span style="font-size:90%>A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).</span>
+<span style="font-size:90%>As trophozoites of ''P.vivax'' mature, they lose their ring form and acquire an irregular form that is said to resemble an amoeba with extended processes. Other features of the species such as enlarged irregular red cells and typical Schuffner's dots also develop at the same time. This form is fairly specific for ''P.vivax'' that is helpful to indicate this diagnosis. Early signs may be seen in early trophozoites.
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Admin at 17:14, 12 December 2024

2024-12-12T17:14:59Z

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	\|style = "font-size:110%; color:black; background: gainsboro \|'''Navigation'''</br>		\|style = "font-size:110%; color:black; background: gainsboro \|'''Navigation'''</br>
	\|-		\|-
	\|<span style="font-size:110%">>[[~~Plasmodium_falciparum~~:_Morphology\|Previous Page]]''</span></br>		\|<span style="font-size:110%">>[[Plasmodium_vivax:_Morphology\|Previous Page]]''</span></br>
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	\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''~~Malaria Pigment~~''' (haemozoin)</span>		\|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"\|<span style="color:black>'''Amoeboid forms''' (haemozoin)</span>
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	<gallery mode="nolines" widths="220px" heights="220px" >		<gallery mode="nolines" widths="220px" heights="220px" >
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	~~<span style=font-size:90%>~~'''~~Description~~'~~''</span>~~		The late trophozoite of ''P.vivax'' becomes more solid, but with an irregular form that is said to resemble an amoeba with extended processes. Other features of the species will also be detected.
	~~<span style="font-size:90%>During their development malarial parasites metabolise the haemoglobin within erythrocytes~~ to ~~support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin~~. ~~As part of that process the parasite must "detoxify" the iron component~~ of the ~~haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development~~.~~</span>~~


	<span style="~~font-size~~:~~90%~~>'''Species significance'''</span>
	<span style="~~font-size~~:~~90%~~>Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''~~P.malariae~~''). ~~Generally however, the form of the pigment is less useful than other features in determining species~~.</~~span~~>
			<span style="color:navy>'''Species significance'''</span>


			A fairly specific feature of ''P.vivax'' that is helpful to indicate this diagnosis. The form develops as the parasites mature and early signs may be seen in early trophozoites.


			<span style="color:navy>'''Additional images'''</span>


			<gallery mode="nolines" widths="220px" heights="220px" >
			File:MAm1.jpg\|A\|link={{filepath:MAm1.jpg}}
			File:MAm3.jpg\|B\|link={{filepath:MAm3.jpg}}
			</gallery>


			Amoeboid forms - an early trophozoite begins to become more irregular though still a partly recognisable "ring" (A), a late trophozoite developing a more typical solid irregular form (B)

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2024-12-12T17:12:14Z

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{| class="wikitable" style="widthe:90%; border-style: solid; border-width: 4px; border-color:teal"
|colspan="1" style = "font-size:140%; color:black; background: FFFAFA"|'''Malaria Pigment''' (haemozoin)
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<gallery mode="nolines" widths="220px" heights="220px" >
File:Pig1.jpg|link={{filepath:MPi1.jpg}}
</gallery>

A solid and angular late trophozoite form of ''P.malariae''. Note the golden pigment in separate clumps of granules distributed over the parasite surface (arrowed).

'''Description'''
During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth. Evetually infected cells at late stages of parasite development red cell may have no visible haemoglobin. As part of that process the parasite must "detoxify" the iron component of the haem element. This process creates a detoxified iron containing protein "haemozoin" which is visible as pigment - as you might expect this is most visible at late stages of parasite development.

'''Species significance'''
Pigment may vary in colour and may be clumped or scattered as individual small masses depending on species; in some instances this can help (most obviously in the central clump seen in the "daisy head" schizonts of ''P.malariae''). Generally however, the form of the pigment is less useful than other features in determining species.

'''Additional images'''
Pigment in different stages of parasite development

<gallery mode="nolines" widths="220px" heights="220px" >
File:Pig2.jpg|Gametocyte ''P.malariae''|link={{filepath:Pig2.jpg}}
File:Pig3.jpg|Schizont ''P.ovale''|link={{filepath:Pig3.jpg}}
File:Pig4.jpg|Trophozoite ''P.ovale''|link={{filepath:Pig4.jpg}}
File:Pig5.jpg|Gametocyte ''P.falciparum''|link={{filepath:Pig5.jpg}}
</gallery>